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Chetan Raj Singh
Dr. Tara Chand
Ashish Jain
Priyanka
Suresh Kumar
Keywords:
Psoriasis, Autoimmune skin disorder, Plaque psoriasis, Guttate psoriasis, Erythrodermic psoriasis, Herbal gel formulation, Aloe barbadensis (Aloe vera), Azadirachta indica (Neem), Phytochemical screening, Topical drug delivery system, Anti-inflammatory activity, antimicrobial properties, Polyherbal formulation, Dermatology, Patient compliance.
Abstract:
Psoriasis is a chronic autoimmune and inflammatory skin disorder characterized by abnormal epidermal differentiation and hyperproliferation. Conventional therapies often lead to systemic side effects and poor patient compliance, creating a need for safer alternatives. Herbal remedies such as Aloe barbadensis (Aloe vera) and Azadirachta indica (Neem) have demonstrated anti-inflammatory, antimicrobial, antioxidant, and wound-healing properties, making them promising candidates for topical formulations. In this study, a polyherbal gel containing Aloe vera and Neem extracts was formulated using Carbopol 940 as a gelling agent, with excipients including propylene glycol, EDTA, methyl paraben, TEA, and ethanol. Phytochemical screening confirmed the presence of alkaloids, glycosides, flavonoids, tannins, saponins, and triterpenoids in the extracts. The prepared gel was evaluated for its physicochemical properties, stability, and therapeutic potential in psoriasis management. Results suggest that the polyherbal gel offers a safe, effective, and patient-friendly alternative for topical treatment of psoriasis.
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International Journal of Recent Research and Review
ISSN: 2277-8322
Vol. XIX, Issue 2
June 2026
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PUBLISHED
June 2026
ISSUE
Vol. XIX, Issue 2
SECTION
Articles
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