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Akshada Vijay Abhang
Keywords:
Magnificence, Small molecule, inhibitors, oncology, hematological, resistance, tyrosine kinases.
Abstract:
Small molecule inhibitors have emerged as a pivotal magnificence of focused remedies in oncology, offering new avenues for the treatment of numerous cancers. These sellers are designed to selectively inhibit precise molecular pathways that pressure tumor boom and progression, thereby offering a extra specific technique to cancer therapy in comparison to traditional chemotherapy. This overview pursuits to offer a comprehensive evaluate of small molecule inhibitors utilized in cancer treatment, focusing on their mechanisms of action, molecular goals, and medical packages. Key focused pathways consist of tyrosine kinases, serine/threonine kinases, and epigenetic regulators, amongst others. The healing implications of these inhibitors are explored throughout a number malignancies, inclusive of solid tumors and hematological cancers. The assessment additionally discusses resistance mechanisms, aspect consequences, and aggregate strategies to conquer limitations and decorate efficacy. As studies advances, small molecule inhibitors keep to enlarge the healing panorama, providing the capacity for personalised medicinal drug and improved affected person consequences in oncology. This paper aims to summarize current information even as highlighting rising trends and future instructions within the improvement of small molecule-focused treatment options for most cancers treatment.
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International Journal of Recent Research and Review
ISSN: 2277-8322
Vol. XVIII, Issue 1
March 2025
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PUBLISHED
March 2025
ISSUE
Vol. XVIII, Issue 1
SECTION
Articles
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