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Manoj Gupta
Mayank Bansal
Priya Sharma
Sunil Sain
Keywords:
Tizanidine, Oral Dissolving Film, HPMC, Drug Release, Patient Compliance.
Abstract:
This study focuses on the design, development, and evaluation of an oral dissolving film (ODF) containing Tizanidine, a centrally acting muscle relaxant. The aim was to enhance patient compliance by providing a fast-dissolving, convenient dosage form. The ODF was formulated using hydroxypropyl methylcellulose (HPMC) as the film-forming polymer, glycerine as a plasticizer, and appropriate sweeteners and flavors to improve palatability. The films were evaluated for their physicochemical properties, drug release profile, and stability. The results indicated that the optimized ODF formulation provided rapid drug release, satisfactory mechanical properties, and good stability, making it a viable alternative to conventional oral dosage forms.
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International Journal of Recent Research and Review
ISSN: 2277-8322
Vol. XVII, Issue 1
March 2024
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PUBLISHED
March 2024
ISSUE
Vol. XVII, Issue 1
SECTION
Articles
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